Initial white blood cell WBC count. Some studies have reported that the prognostic factors of ICU mortality in patients with RD included high APACHE II and SOFA scores serious infection mechanical ventilation vasopressor renal replacement therapy and glucocorticoid dose 6 7 9 11 12 17 28.
However these factors predicting outcome are poorly defined.
Prognostic factors of all. Prognostic factors for children with ALL Age at diagnosis. Children between the ages of 1 and 9 with B-cell ALL tend to have better cure rates. Initial white blood cell WBC count.
Children with ALL who have very high WBC counts greater than 50000 cells per. Prognostic factors for ALL Age. Among adults younger patients tend to have a better prognosis than older patients.
There is no set cutoff for. Initial white blood cell WBC count. People with a lower WBC count less than 30000 for B-cell ALL and less than.
Gene or chromosome abnormalities. Prognostic and predictive factors for ALL Age. Younger adults usually those younger than 50 years of age have a more favourable prognosis than older adults.
White blood cell count. The white blood cell WBC count at the time of diagnosis is a prognostic factor for ALL. The prognostic factors for newly diagnosed patients with acute lymphoblastic leukaemia ALL are broadly divided into those present at diagnosis and those that only become apparent once the time to achieve a complete remission CR and the degree of minimal residual disease MRD have been determined at various time points.
A prognostic factor is one that influences the outcome independently of treatment and a predictive factor is one with a relationship to the response to a particular therapy. The most important prognostic factors include axillary lymph node status tumor size estrogen and progesterone receptor status and HER2neu protein overexpression or gene amplification. Thus ALL remains a challenging disease to treat in the AYA and adult populations.
A major contributing factor that influences prognosis in this population is the reduced prevalence of genetic subtypes associated with favorable outcome and a concomitant increase in subtypes associated with poor outcome. There is controversy regarding the prognostic significance of several factors in TALL including early Tcell precursor ETP phenotype and various recurrent genomic aberrations. We aimed to evaluate the efficacy and safety and identify the impact of prognostic factors minimal residual disease MRD baseline white blood cell WBC count cytogenetics cerebrospinal fluid CSF status toxicities and infections on survival outcomes.
Prognostic and predictive factors are important for estimation of prognosis clinical decision making and trial design and are key in a transition towards more personalised medicine. A variety of factors have been described in past trials on palliative treatment of oesophagogastric cancer and available prognostic indexes use different sets of factors which are based on relatively small. Here are the prognostic factors.
The classic ones include the TNM staging. The size of the tumor the nodal status and the presence or lack thereof of a distant metastatic site. Histologic grade has been well tested but it is very operator-dependent.
Histology subtype is a little easier to define. Prognostic factors for ALL include age older than 30 y worse with increasing age White blood cells WBC 30000mm 3 for B-cell ALL. WBC 100000mm 3.
The prognostic factors in acute leukemia have undergone a major change over the past decade and are likely to be further refined in the coming years. While age is the single most important prognostic factor in both AML and in ALL recurring cytogenetic abnormalities and molecular markers have become crucial for the prognosis of patients and for new directions in the development of targeted therapies. To study the prognostic factors of adult patients with T-lymphoblastic lymphoma T-LBL and to evaluate therapeutic effects of acute lymphoblastic leukemia ALL-type chemotherapy in combination with allogeneic hematopoietic stem cell transplantation allo-HSCT in patients who achieved overall response OR with first line ALL-type chemotherapyThis was a retrospective study of 59 adult.
Knowledge of physical prognostic factors such as quadriceps strength is crucial to inform rehabilitation and has important implications for outcome following ACL reconstruction. However these factors predicting outcome are poorly defined. Factors that predict a better outcome are called good or favorable prognostic factors.
Those that predict for worse outcomes are called poor prognostic factors. For some diseases and conditions such as non-Hodgkin lymphomas the factors are scored to give a prognostic index. 1 Prognostic Factors in Lymphoma.
Prognostic factors were divided into patient variables disease characteristics and chemical or imaging markers. Outcomes were divided into clinical progression radiographic progression or indication for receiving a THR. If outcomes were measured at several follow-up.
Some studies have reported that the prognostic factors of ICU mortality in patients with RD included high APACHE II and SOFA scores serious infection mechanical ventilation vasopressor renal replacement therapy and glucocorticoid dose 6 7 9 11 12 17 28.